气候干燥的玻利维亚高地，一对年迈的、以放牧羊驼为生的克丘亚族夫妇一直在这里过着相濡以沫的生活。但一场多年难遇的大旱灾让他们本就拮据的生活雪上加霜，这不仅威胁到他们自己，还威胁到整个村庄的存亡。夫妻俩的孙子闻讯从城市返回，想让他们与自己一起进城生活，但这对早已习惯乡村生活的夫妻俩来说，又是一个严酷的挑战。两代、三人将以不同的方式看待社会与自然的变化，以及生命的意义。

California gold rush, late 1800's: A gun slinging bounty hunter (Mortimer) travels deep into the mountains to find a deadly Apache warrior (Brother Wolf) who is wanted by the law. Along the way he passes through a gold mining Town. The miners help direct Mortimer to the Apache and send him on his way. Mortimer enters the forest and begins to track the Apache. Back in town, the miners un-earth an ancient meteor. They use their pick axes to crack it open. A section of the meteor splits apart and spores explode out of it. The spore surround and infect the entire population of the mining camp. They are transformed into ravenous mutants. After a vicious battle against the Apache warrior, Mortimer exits the forest with his prisoner in shackles. They hike back to the mining town to find them selves surrounded by a horde of blood thirsty mutants. Now Mortimer the gun slinger and Brother Wolf the Warrior must join together to survive the mutant hordes. What ensues is a bloodbath of horror for the Dead and the Damned.