Brother's Blood takes place on the mean streets of a city in decay, where a recently released convict begins to take murderous revenge against his childhood friends, whom he believes let him take the fall for a crime they collectively committed. As the bodies start piling up, one of the friends, now a cop, will stop at nothing to put an end to the murderous rampage and to right...

唐（帕特里克·威尔森 Patrick Wilson 饰）和妻子莫娜（凯瑟琳·海格尔 Katherine Heigl 饰）结婚多年，两人共同养育了两个可爱的孩子。在同事和朋友们眼中，唐拥有着楷模般的幸福生活，可实际上，只有唐自己知道，莫娜是一个丧心病狂的控制狂和独裁者，自己生活中的点点滴滴，都在妻子的计划和控制之中。