After a global neurological epidemic, those who remain search for meaning and connection in a world without memory.

男青年威尔（马特•兰特尔 Matt Lanter 饰）从一场诸多电影情节和明星串联而成的噩梦中惊醒，发现这天正是他梦中显示的世界末日——2008年8月29日。威尔不能确定与女友艾米（凡妮莎•米尼洛 Vanessa Minnillo 饰）的关系，后者愤而离去。为了弥补遗憾，已经25岁的威尔为自己举办甜蜜16岁的生日派对，这场疯狂派对变成了一场无尽恶搞电影的狂欢，所谓乐极生悲，狂欢中的人们突然发现城市已经陷入地动山摇陨石坠落的大灾难之中，混乱中威尔和艾米失散了，为了找回真爱，威尔偕同加尔文与女友、怀孕的朱妮踏上了前往博物馆解救艾米的旅程，一路上绿巨人、钢铁侠等英雄纷纷被灾难击溃，威尔一伙儿也连续击败欲望都市女郎、魔法奇缘王子等人，在这场无厘头电影中向博物馆前进。

Brett Blackmore is a high school senior whose exemplary GPA and college resume hides the fact that he's unintentionally sold his childhood for a future he's not even sure he wants. When his high-school senior prank goes wrong, his life crumbles before his eyes. In frustration he launches the F**k-It List - of all the things he wishes he'd done but was too afraid. The list goes viral and touches a nerve with teenagers everywhere, exposing the educational-industrial complex as a money-machine designed to encourage anxiety-ridden parents to sell their kids into years of Tiger-Mom style servitude. Brett decides he's going to break free - and make a run for a future of his own design.