霍金（埃迪·雷德梅恩 Eddie Redmayne 饰）和简（菲丽希缇·琼斯 Felicity Jones 饰）相识于一场舞会上，两人初次见面交谈甚欢，颇有一番相见恨晚的意味。之后，霍金大胆的邀请简参加舞会，二人以此为契机，陷入了热恋之中。

A man's struggle against himself and against time. Kenyan runner Eliud Kipchoge dreams of completing a marathon distance of less than two hours. An achievement that is considered unattainable for a human being. Here we follow him as he prepares to break the impossible record. Is he able to break the magical two-hour limit and write history?

故事聚焦在一支研究团队，他们被派到科拉深孔（Kola Superdeep Borehole）去调查源自于深处的奇怪声音，他们却发现超乎他们所有想像的东西。更糟的是，他们可能无意间将躲藏在深处的东西给释放了出来。